Rocuronium Bromide Injection
Indication:
This product is indicated as an adjunct to general anesthesia to facilitate endotracheal intubation during routine sequence induction and to provide skeletal muscle relaxation during surgery.
Dosage and Administration:
This product needs to be administered intravenously, which can be intravenous injection or continuous infusion.
Dosage:
As with other neuromuscular blocking agents, the dosage of rocuronium bromide should be individualized in each patient. The following factors should be taken into account when determining the dose:
The method of anesthesia, the expected duration of surgery, the method of sedation, the expected duration of mechanical ventilation, the possible interaction with other drugs that are administered concomitantly, and the condition of the patient. The use of an appropriate neuromuscular monitoring technique is recommended for the evaluation of neuromuscular block and recovery.
Inhalational anesthetics do potentiate the neuromuscular blocking effects of rocuronium bromide.This potentiation however, becomes clinically relevant in the course of anesthesia, when the volatile agents have reached the tissue concentrations required for this interaction. Consequently, adjustments should be made by administering smaller maintenance doses at less frequent intervals or by using lower infusion rates of rocuronium bromide during long lasting procedures (longer than 1 hour) under inhalational anaesthesia. (see [Drug Interactions])
In adult patients the following dosage recommendations may serve as a general guideline for tracheal intubation and muscle relaxation for short to long lasting surgical procedures.
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