Carbamazepine Tablet 200mg, 10′sx10/Box, GMP Medicine

• Application: Antipyretic, Analgesic
• Usage Mode: For oral administration
• Suitable for: Children, Adult
• State: Solid
• Shape: Tablet
• Pharmaceutical Technology: Chemical Synthesis
• Model NO.: AMC12010
• Shelf-Life: 3 Years
• Transport Package: 200mg, 10X10′s/Box
• Specification: 200mg, 10x10′s/box
• Trademark: Medipharm; Shinepharm; OEM
• Origin: China
• HS Code: 3004909099
• Production Capacity: 1000000box

Product Description

Product Description

Characteristics:
This product is white piece.
Indications:
1. Complex partial seizures (also known as psychomotor seizures or temporal lobe epilepsy), generalized tongue-array twin seizures, the above two mixed seizures or other partial or systemic seizures; It has no effect on typical or atypical absence attacks, muscle twins or absence tension attacks.
2. Trigeminal neuralgia and glossopharyngeal neuralgia are also used as long-term prophylactic drugs after trigeminal neuralgia relief. It can also be used for tuberculosis and multiple sclerosis, diabetic peripheral neuralgia, limb pain and post-traumatic neuralgia and post-herpetic neuralgia.
3. Prevention or treatment of manic-depression; Manic-depressive disorder that does not respond to or cannot be tolerated by lithium or antipsychotics or antidepressants may be used alone or in combination with lithium and other antidepressants.
4. Central partial diabetes insipidus can be used alone or chlorpropiuron or clobebutyl ester.
5. Some psychiatric disorders include schizophrenia affective disorder, intractable schizophrenia and out-of-control syndromes associated with limbic system dysfunction.
6. Restless leg syndrome (Ekbom syndrome), hemifacial spasm.
7. Withdrawal syndrome of alcoholism.
Usage And Dosage:

Normal adult dosage
1. Anticonvulsion, start with 0.1g, 2-3 times a day; After the second day, 0.1g was added daily until the curative effect appeared. The maintenance amount should be adjusted to the lowest effective amount and taken in separate doses. Pay attention to individual, the maximum daily dose should not exceed 1.2g.
2. Analgesia, 0.1g at the beginning, twice a day; After the second day, 0.1-0.2 g should be added every other day until the pain is relieved. The maintenance dose should be 0.4 to 0.8g per day. The maximum dose does not exceed 1.2g per day.
3. Diabetes insipidus, 0.3 ~ 0.6g per day when used alone, if combined with other antidiuretics, 0.2 ~ 0.4g per day, divided into 3 times.
4. Anti-dryness or anti-psychosis, start with 0.2-0.4g a day, gradually increase to a maximum of 1.6g a week, divided into 3 to 4 times. Daily limit, 12 to 15 years old, not more than 1g; No more than 1.2g for 15 years old or older; A few use up to 1.6g. The limit is usually 1.2g for adults, up to 1g a day for 12 to 15-year-olds, and up to 1.6g for a few. Analgesic use should not exceed 1.2g per day.
Normal dosage for children
For anticonvulsion, the dosage was increased every 5 to 7 days to 10 mg/kg per body weight before 6 years old, and increased to 20 mg/kg if necessary. The maintenance dosage was adjusted to maintain blood concentration of 8 to 12 μg/kg, generally 0.25 to 0.3g, not more than 0.4g per body weight of 10 to 20 mg/kg. For children aged 6-12, 0.05 g to 0.1g should be taken twice on the first day, and 0.1g should be increased every other week until the curative effect appears. The maintenance dose should be adjusted to the minimum effective dose, usually 0.4 to 0.8g per day, not more than 1g, divided into 3 to 4 times.
Interactions:
1. When used together with acetaminophen, especially if it is overdosed for a single time or in large quantities for a long time, the risk of liver poisoning increases and the efficacy of the latter may be reduced.
2. When combined with coumarin anticoagulants, due to the positive induction effect of liver enzyme of this product, the blood concentration of anticoagulants is reduced, the half-life is shortened, and the anticoagulant effect is weakened. Prothrombin time should be measured and the dosage adjusted.
3. In combination with carbonic anhydrase inhibitors, the risk of osteoporosis is increased.
4. Due to the liver enzyme induction effect of this product, it can strengthen the antidiuretic effect when combined with chlorsulfonpropiourea, clobebutyl ester (antamine), desmopressin, lypressin, pituitrin, vasopressin, etc., and the dosage of each drug combined should be reduced.
5. When used in combination with estrogen-containing contraceptives, cyclosporine, digitalis (with the possible exception of digoxin), estrogen, levothyroxine, or quinidine, the effects of these drugs are reduced due to positive induction of liver metabolic enzymes by carbamazepine, and the dosage should be adjusted to oral contraceptives containing only progesterone (progesterone). Heavy vaginal bleeding may occur when used with oral contraceptives.
6. Concomitant with doxycycline (doxycycline), whose blood concentration may be reduced and whose dosage may be adjusted as necessary.
7.Erythromycin, Troleandomycin and Detropropoxyphene can inhibit the metabolism of carbamazepine, resulting in the increase of blood concentration of carbamazepine and toxic reactions.
8. Haloperidol, loxapine, maprotiline, thiatholites, or tricyclic antidepressants can enhance the metabolism of carbamazepine, resulting in elevated blood concentration and toxic reactions of the latter.
9. Lithium reduces the antidiuretic effect of carbamazepine.
10. When used in combination with monoamine oxidase (MAO) inhibition, hyperthermia or/or hypertensive crisis, severe convulsions, and even death may occur at least 14 days apart. When carbamazepine is used as an anticonvulsant, MAO inhibitors can alter the type of epilepsy.
11.Carbamazepine reduces absorption of nomifensine and speeds its elimination.
12. Pheno.barbitall and phenytoin accelerate the metabolism of carbamazepine, reducing the T1/2 of carbamazepine to 9-10 hours.
Storage:
Shade and keep sealed.
Expiry Date:
36 months
 

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