Amikacin Sulfate Injection
| Name |
Amikacin Sulfate Injection |
| Specidication |
100mg/2ml, 1's/box |
| Shelf Life |
3 years |
| Brand |
Medipharm or OEM |
| Origin |
China |
Indications:
Amikacin sulfate injection, the indication for this product is suitable for severe infection caused by Pseudomonas aeruginosa and some other pseudomonas, Escherichia coli, Proteus, Klebsiella, Enterobacter, Serrella, Acinetobacter and other sensitive gram-negative bacilli and Staphylococcus (methicillin-sensitive strains). Such as bacteremia or septicemia, bacterial endocarditis, lower respiratory tract infection, bone and joint infection, biliary tract infection, abdominal infection, complex urinary tract infection, skin and soft tissue infection, etc.
Because it is stable to most aminoglycoside inactivating enzymes, it is especially suitable for the treatment of severe infections caused by gram-negative bacilli that are resistant to kanamycin, gentamicin or tobramycin.
Side effects:
1. Patients may develop hearing loss, tinnitus or a feeling of fullness in the ears. A few patients may also have symptoms such as vertigo and unsteady gait. Hearing loss generally does not worsen after withdrawal, but some may progress to deafness after withdrawal.
2. This product has a certain degree of renal toxicity, patients can appear hematuria, reduced frequency of urination or reduced urine volume, blood urea nitrogen, blood creatinine value increased. Most of the symptoms were reversible, with immediate relief after withdrawal, but there were also isolated reports of renal failure.
3. Weakness, lethargy, dyspnea and other neuromuscular blocking effects are rare.
4. Other adverse reactions include headache, numbness, acupuncture infection, tremor, convulsion, joint pain, drug fever, eosinophilia, abnormal liver function, blurred vision, etc.
Usage & Dosage:
1. For adults, intramuscular injection or intravenous drip. Patients with simple urinary tract infection who were resistant to commonly used antibiotics were 0.2g (1 dose) every 12 hours; For other systemic infections 7.5mg/kg every 12 hours, or 15mg/kg every 24 hours. Adults should not exceed 1.5g (7.5 pills) per day, and the course of treatment should not exceed 10 days.
2. For children, intramuscular injection or intravenous drip. The first dose is 10mg/kg body weight, followed by 7.5mg/kg every 12 hours, or 15mg/kg every 24 hours.
3. Patients with renal dysfunction: creatinine clearance of 50 to 90ml/min were given 60% to 90% of the normal dose (7.5mg/kg) every 12 hours; Creatinine clearance of 10 to 50ml/min with 7.5mg/kg every 24 to 48 hours of 20% to 30%.
Storage instructions:
Store below 25ºC. Protect from moisture. Keep out of reach of children.
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