| Customization: | Available |
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| Application: | Internal Medicine |
| Usage Mode: | For oral administration |
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Dexa Methason + Neomycin Sulphate Eye Drop
COMPOSITION:
Each mI contains:
Neomycin sulphate USP eq 3.5mg
Dexa Methason Phosphate USP eq. Phosphate 1mg
PHARMACOLOGICAL CLASSIFICATION:
Combination antibiotics and corticosteroids.
PHARMACOLOGICALACTION:
Neomycin sulphate is a broadspectrum antibiotic. Gram-negative species that are highly sensitive are E.coli, Enterobacter, Aerobacter, aerogenes, K.pneumoniae, Pasteurella, Pr. vulgaris, Salmonella, Shigella, H. influenzae, N. meningitidis, V. choleraeand B. pertussis. Gram-positive microorganisms thatare inhibited include Bacillus anthracis, C. diphtheriae, Staph. aureus, Stre. faeca lis, List. Monocytogenes and M. tuberculosis. Borelia and Leptospira interrogans are also suppressed.The sensitivity of Pseud. aeruginosa is variable. Neomycin is active against tubercle bacilli, regardless of their susceptiblity to streptomycin.
INDICATIONS:
In the management of infectous ocular inflammations produced by organisms which are sensitive to the antibiotics neomycin sulphate. Acute or chronic nonpurulent conjunctivitis, blepharoconjunctivitis and keratoconjunctivitis; non-specific superficial keratitis; deep keratitis; acne rosace keratitis; iridocyclitis; mild acute iritis, recurrent marginal ulceration and corneal ulcer (use with care In those diseases causing thinning of the cornea because of the danger of perforation); non-purulent blepharitis; scleritis; episcleritis; scleroconjunctivitis; herpes zoster ophthalmicus (do not use in herpes simplex); and post; operatively to aid in the prevention of ophthalmic cases of infections.
WARNINGS :
1.If irritation persists or increases, discontinue the use and consult physician.
2.Do not touch the dropper tip or other dispensing tip to any surface since this may contaminate the solution.
CONTRA-INDICATIONS:
Contra-indicated in tubercular, fungal and most viral lesions of the eye (herpes simplex-dendritic keratitis); vaccinia varicella, acute purulent conJunctivitis and acute purulent blepharitis and in those persons who have shown hypersensitivity to any of its components. Mechanical lacerations and abrasions.
DOSAGE AND DIRECTIONS FOR USE:
Instil one to two drops topically in the conjunctival sac(s) four to six times daily. Dosage may be reduced after three to four days when satisfactory improvement has been obtained.
SHAKE BOTTLE WELL BEFORE USE.
SIDE EFFECTS AND SPECIAL PRECAUTIONS
Corticosteroids delay wound healing,promote development and spread of infection and may mask evidence of its progression until sight is lost. Perforation has been known to occur with the use of topical steroids in those diseases of the eye which cause thinning of the cornea or sclera.
Employment of steroid medication in the treatment of stromal herpes simplex requires great caution; frequent slit lamp microscopy is mandatory.Steroid medication may give rise to serious exacerbations of herpes infections of the eye.
Prolonged use may result in glaucoma, damage to the optic nerve, defects in visual acuity and fields of vision, posteri or subcapsular cataract formation, or may aid in the establishment of secondary ocular infection from the pathogens liberated from ocular tissue.
As fungal infections of the cornea are particularly prone to develop coincidentally with long-term topical steroid applications, fungus invasion must be suspected in any persistent corneal ulceration where a steroid has been used or is In use.
Prolonged use may give rise to the development of iatrogenic glaucoma. Intraocular pressure should be monitored frequently. If the eye has not responded within 48 hours, the patient should be referred to an ophthalmologist because of the possibility of inducing corneal abscess, fungal keratopathy or glaucoma.
Prolonged local use of neomycin should be avoided as it may lead to sensitisation.
KNOWN SYMPTOMS OF OVERDOSAGE AND
PARTICULARS OF ITS TREATMENT:
As for side effects and special precautions above. Discontinue use immediately.
PRESENTATION:
Available as 10 ml sterile plastic bottle.
STORAGE INSTRUCTIONS:
Keep in a cool place, below 25ºC. Keep out of reach of Children.
Do not use more than 30 days after opening.
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