Hyoscine Butylbromide Injection

• Customization: Available
• Type: Biological Products
• Pharmaceutical Technology: Chemical Synthesis
• Model NO.: AMC14014
• Printing: Ceramic
• Shelf Life: 3 Years
• OEM: Available
• Registration Dossiers: Available
• Transport Package: 100′s/Box
• Specification: GMP
• Trademark: Medipharm, OEM
• Origin: China
• HS Code: 30042090
• Production Capacity: 50000 Boxes Per Month

Product Description

Hyoscine Butylbromide Injection
 

Description
 It is a sterile solution. Hyoscine Butylbromide in water for injections.Each ampoule
contains Hyoscine Butylbromide 20mg or each ampoule contains Hyoscine Butylbromide
lOmg.
 
INDICATIONS:
Hyoscine is a tertiary amine antimuscarinic agent with central and peripheral actions.lt
is a more powerful suppressant of salivation than atropine,and usually slows rather than
increases heart rate,especially in low doses.Its central action differs from that of atropine in
that it depresses the cerebral cortex and produces drowsiness and amnesia.Hyoscine
butylbromide is quaternary ammonium derivatives.
Hyoscine is effective in the prevention and control of motion sickness and has also
been given as an antiemetic in the prophylactic treatment of other forms of nausea.Hyoscine
is also given to prevent motion sickness via a transdermal delivery system which is placed
behind the ear and supplies 500 <xg over 3 days.
 
ADVERSE EFFECTS AND PRECAUTIONS:
In contrast to atropine,hyoscine produces central depression at therapeutic doses and
symptoms include drowsiness and fatigue.Toxic doses of hyoscine produce stimulation of
the CMS in a similar manner to atropine.However,hyoscine does not stimulate the medullary
centres and therefore does not produce the increases in respiration rate or blood pressure
seen with atropine.Hyoscine may produce CNS stimulation rather than depression at
therapeutic doses if used in the presence of pain without opioid analgesics; symptoms include
excitement,restlessness,hallucinations,or delirium.
Hyoscine should not be used concurrently wih CNS depressants.Caution has been advised
in elderly patients and in patients with impaired metabolic,liver,or kidney function,as adverse
CNS effects have been stated to be more likely in these patients.There have been rare reports
of an increase in frequency of seizures in epileptic paticnts.The quaternary derivatives, such
as the butylbromide do not readily cross the blood-brain barrier,so central effects are rare.
 
ADMINISTRATION:
Hyoscine has been given as its quaternary ammonium derivatives in conditions
associated with visceral spasm,in usual doses of 20 mg of the butylbromide intramuscularly
or intravenously,repeated after 30 minutes if necessary.The use of antimuscarinics in the
relief of visceral spasms of the gastrointestinal tract is discussed on;they may also relieve
painful spasms of the biliary and genitourinary systems,although analgesics are normally
used.
 
AVAILABILITY:
Ampoule of Iml-box of 100 ampoules.
STORAGE:
Preserve in well closed container,prolected from light and stored in a
cool place.