Magnesium Sulfate Injection
| Name |
Magnesium Sulfate Injection |
| Specidication |
2.5g/10ml, 10's/box, 100boxes/ctn |
| Ctn Size |
57*45*24cm |
| Brand |
Medipharm or OEM |
| Origin |
China |
Indications:
It can be used as an anticonvulsant. It is often used for pregnancy-induced hypertension. It lowers blood pressure, treats preeclampsia and eclampsia, and is also used to treat premature births.
Contra-indications:
1. Intravenous injection of magnesium sulfate often causes flushing, sweating, dry mouth and other symptoms, rapid intravenous injection can cause nausea, vomiting, palpitation, dizziness, individual nystagmus, slow down the injection speed symptoms can disappear.
2. Renal insufficiency and high dosage can cause blood magnesium accumulation. When the blood magnesium concentration reaches 5mmol/L, muscle excitability can be inhibited, sensory response is dull, knee tendon reflex disappears, and breathing begins to be inhibited. When the blood magnesium concentration reaches 6mmol/L, respiratory arrest and arrhythmia can occur, and heart block can be caused by further increase of the concentration.
3. Continuous use of magnesium sulfate can cause constipation, some patients may appear paralytic intestinal obstruction, improved after withdrawal.
4. In very few cases, hypocalcemia appears.
5. Magnesium ions can freely pass through the placenta, resulting in neonatal hypermagnesia, manifested as low muscle tone, poor sucking ability, inactivity, crying is not loud, and a few have respiratory depression.
6. A few pregnant women developed pulmonary edema.
Usage & Dosage:
1. Treatment of moderate to severe gestational hypertension, preeclampsia and eclampsia
The first dose was 2.5-4G, diluted with 25% glucose injection 20ml, slowly injected intravenously within 5 minutes, and then maintained by 1-2g intravenous drip every hour. The 24-hour total was 30g and was monitored based on knee tendon reflexes, breathing and urine volume.
2. Treatment of preterm birth and treatment of pregnancy-induced hypertension
The dosage and method were similar, and the initial loading was 4g. Diluted with 25% glucose injection 20ml, intravenous injection was given slowly within 5 minutes, followed by 25% magnesium sulfate injection 60ml, added to 5% glucose injection 1000ml intravenously, at a rate of 2g per hour, until 2 hours after contraction stopped, and then oral βadrenoreceptor agonists were maintained.
Storage instructions:
Store below 25ºC. Protect from moisture. Keep out of reach of children.
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