Powder: | Yes |
---|---|
Customized: | Customized |
Certification: | GMP, USP, BP, Ep |
Description :
English name: Cefoperazone Sodium
Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, (6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, [6R-[6a,7b(R*)]]-;Bioperazone;CP 52640-2;Cefobis;Cefogram;Cefomycin;Cefoneg;Cefoperazone sodium;Cefoperazone sodium salt;Cefosint;Dardum;Farecef;Kefazon;Myticef;Novobiocyl;Pathozone;Peracef;Sodium cefoperazone;
Specification:98%
CAS NO.: 62893-20-3
Appearance: Faint beige powder
Molecular weight: 668.72
Molecular formula: C25H27N9O8S2. Na
Melting point: 200-202 °C
Application :
1.Usage Broad spectrum third generation cephalosporin antibiotic. An antibacterial.
2. Usage antidepressant, serotonin reuptake inhibitor, 5HT1A agonist
Specification:
Item |
Specification |
Test Results |
Description |
White crystal or slightly yellow hygroscopic powder |
Conforms |
Identification |
IR: Similar to the reference standard HPLC: Similar to the reference standard I t gives reaction of sodium |
Conforms Conforms Conforms |
Solubility |
Freely soluble in water, soluble in methanoll,slightly soluble in ethanol |
Conforms |
Appearance of solution |
10% solution is clear Absorbance: NMT 0.15 |
Conforms 0.05 |
pH |
4.5 to 6.5 |
5.1 |
Water |
Not more than 5.0% |
3.0% |
Related substances |
Any individual impurity: NMT 1.5% Total impurities:NMT 4.5% |
0.4% 1.3% |
Acetonee |
NMT 2.0% |
1.2% |
Heavy metals |
NMT 5ppm |
Conforms |
Sterility |
Meets the requirements |
Conforms |
Bacterial endotoxins |
Less than 0.20 IU/mg |
Conforms |
Assay (on anhydrous basis) |
95.0% to 102.0% of Cefoperazone sodium on anhydrous basis |
98.1% |
Conclusion: Conform to EP 6.0 |