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Pharmacology
Chloramphenicol works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers.
Chloramphenicol therefore controls the infection and remaining bacteria die or are killed by the body's immune system.
Chloramphenicol ear drops are administered into the ear to treat various types of bacterial ear infections. Putting the drops directly into the ear allows the chloramphenicol to act directly on the bacteria that are causing the infection.
Indications
Chloramphenical ear drops are indicated for the short term treatment of infections in otitis externa due to chloramphenicol-sensitive organisms in patients with intact tympanic membranes.
Warnings:
This medicine is not to be taken by mouth.
After administering the ear drops you should lie with the affected ear uppermost for at least ten minutes to avoid the drops running out. After this time you can put some cotton wool into the ear to get on with normal activities.
These ear drops should not be used for longer than one week, as they could possibly become less effective or produce allergic reactions if used over a long period of time.
Any remaining ear drops should be carefully disposed of four weeks after the first opening as they are likely to be contaminated.
Adverse Effects
Sensitisations or allergic reactions.
Dosage & Administration
The dose of otic chloramphenicol will be different for different patients.
Follow your doctors orders or the directions on the label.
The following information includes only the average doses of otic chloramphenicol.
If your dose is different, do not change it unless your doctor tells you to do so.
For infections of the ear canal:
Adults and children Use 2 or 3 drops in the affected ear two to three times a day
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