This compound tablets contain 4 kinds of Calcium Amino Acid, 1 kind of Calcium Hydroxyl-amino Acid and 5 kinds of Amino Acids.
CHARACTERS Compound α-Ketoacid Tablets are yellow film coated. The tablet color is white after film removed. For each tablet, the total nitrogen content is 36mg and the total calcium content reaches 1.25mmol which equals approximately to 50mg.
PHARMACOLOGY AND TOXICOLOGY
Compound α-Ketoacid Tablets can supply the essential amino acids and reduce the intake of ammonia nitrogen. Ketone or hydroxyamino acid does not contain amidogen, which can help them utilize the nitrogen from non-essential amino acids to transfer into amino acids. This can reduce the synthesis of urea as well as the accumulation of the uremic toxic products. Ketone or hydroxyamino does not cause the ultrafiltration of remnant nephron, alleviate the renal hyperphosphatemia and secondary hyperparathyroidism and improve the status of renal osteodystrophy. With the low-protein diet together, Compound α-Ketoacid Tablets can reduce the intake of nitrogen and at the same time avoid the adverse consequences caused by insufficient protein intake and malnutrition.The results of toxicology researches indicate that Compound α-Ketoacid Tablets has low toxicity. Chronic toxicology researches show that minimum toxicity dose of dog is 1200 mg/day and rat 2700 mg/day. After conversion, the dosage for the human body (70 kg) is 84 g/day according to dog dosage and 189 g/day according to rat dosage.
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