PRESENTATION: Aminophylline Tablets BP 100mg: white round tablet plain on both sides. Each table contains: Aminophylline BP 100mg. CLINICAL PHARMACOLOGY: Aminophylline is a bronchodilator, Aminophylline relaxes bronchial smooth muscle, relieves bronchospasm, and has a stimulant effect on respiration. It stimulates the myocardium and central nervous system, decreases peripheral resistance and venous pressure, and causes diuresis. USES: Aminophylline is used in the management of asthma and chronic obstructive pulmonary disease. DOSAGE AND ADMINISTRATION: Acute bronchospasm: 100 to 300mg three or four times daily after food. CONTRA-INDICATIONS AND WARNINGS: Aminophylline should be given with caution to patients with peptic ulceration, hyperthyroidism, hypertension, cardiac arrhythmias or other cardiovascular disease, or epilepsy. Aminophylline should also be given with caution to patients with heart failure, hepatic dysfunction or chronic alcoholism, acute febrile illness, and to neonates and the elderly. Adverse Effects: The adverse effects commonly encountered are gastro-intestinal irritation and stimulation of the CNS. Aminophylline may cause nausea, vomiting, abdominal pain, diarrhoea, other gastro-intestinal disturbances, insomnia, headache , anxiety, restlessness, dizziness, tremor and palpitations. Storage: Store in a cool and dry place. Protect from light. Keep out of reach of children.
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