| Application: | Internal Medicine |
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| Usage Mode: | Injection |
| Suitable for: | Elderly, Children, Adult |
| State: | Liquid |
| Shape: | Oral Liquid |
| Type: | Western Medicines |
| Samples: |
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| Customization: |
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Indications:
This product can neutralize tetanus toxin and can prevent or treat tetanus.
Dosage and Administration:
Usage:
Subcutaneous injection should be performed at the deltoid attachment of the upper arm. When toxoids are injected at the same time, the injection sites must be separated. Intramuscular injection should be performed in the middle of the deltoid muscle of the upper arm or in the upper outer part of the gluteus maximus muscle. Intravenous injection should only be given to patients who do not respond to subcutaneous or intramuscular injection.
Intravenous injection should be slow, starting at no more than 1 ml per minute and then no more than 4 ml per minute. Intravenous injection should not exceed 40 ml at a time, and the body weight of children should not exceed 0.8 ml per 1 Kg. Antitoxins can also be added to glucose injection, sodium chloride injection and other infusions for intravenous drip. Prior to intravenous injection, heat the ampoule in warm water until it approaches body temperature. If abnormal reaction occurs during injection, it is necessary to immediately stop such reaction.
Dosage:
1,Prevention: 1500 ~ 3000 IU is injected subcutaneously or intramuscularly once, and the dosage is the same for children and adults; the dosage can be increased by 1 ~ 2 times in severe cases. After 5 to 6 days, if the risk of tetanus infection is not eliminated, the injection should be repeated.
2,Treatment: The first intramuscular or intravenous injection of 50,000 to 200,000 IU, the same dosage for children and adults; later depending on the condition to determine the injection dose and interval, the appropriate amount of antitoxin can also be injected into the tissue around the wound. Newborn tetanus, 20000 to 100000 IU intramuscularly or intravenously in divided doses over 24 hours.
Storage instructions:
Store at 2-8ºC, protected from light.
| Testing terms | Standards | Results |
| Characteristics | Colorless or yellowish clear solution | Complies |
| Uniformity content | Not less than 0.75ml/amp | Complies |
| Osmotic pressure molar concentration | 260-360m0smol/kg | 318m0smol/kg |
| pH | 6.0-7.0 | 6.4 |
| Protein content | Not more than 100g/L | 39g/L |
| Nacl content | 7.5-9.5g/L | 8.3g/L |
| Ammonium sulfate content | Not more than 1.0 g/L | 0.2g/L |
| M-cresol concentration | Not more than 2.5 g/L | 2.0g/L |
| Residual of Aluminum | Not more than200μg/L | 11μg/L |
| Antibody potency | Not less than 2000IU/ml for Prophylaxis | 2600IU/ml |
| Specific activity | each protein 1g not less than 45000IU for Prophylaxis |
66667IU/gp |
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