| Customization: | Available |
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| Application: | Internal Medicine |
| Usage Mode: | For oral administration |
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COMPOSITION:
Each tablet contains 100 mg Mebendazole.
PHARMACOLOGICAL CLASSIFICATION:
A. 12 Anthelmintics, Bilharzia medicines, filaricides, etc.
PHARMACOLOGICAL ACTION:
Mebendazole is a broad-spectrum anthelmintic, and causes selective disappearance of cytoplasmic microtubules in the tegumental and intestinal cells of affected worms. Secretory substances accumulate in Golgi areas, secretion of acetylcholinesterase and uptake of glucose is impaired, and glycogen is depleted. These effects are not noted in host cells. Immobilization and death of the parasites occur slowly, and clearance from the gastrointestinal tract may not be complete until 3 days after treatment with mebendazole.
INDICATIONS:
Mebendazole is indicated for the treatment of single and mixed helminth infestations caused by:
Ascariasis (roundworm)
-Temidens deminutus -Intestinal capillariasis -Enterobiasis (pinworm)
-Trichuris trichiura (whipworm)
-Ancylostoma duodenale (hookworm)
-Necator americanus (hookworm)
-Strongyloides stercoralis (threadworm)
-Taenia spp (tapeworm)
CONTRA-INDICATIONS:
Mebendazole is teratogenic in experimental animals and should not be given during pregnancy and lactation.
Sensitivity to imidazoles.
DOSAGE AND DIRECTIONS FOR USE:
Fasting and purging is not required.
For infants under 2 years, see "Side-effects and special precautions".
For all worms excluding tapeworm and threadworm:
Dosage for adults and children:
One tablet twice daily (morning and evening) for three consecutive days.
If patient is not cured, 3 weeks after treatment a second course should be given.
STORAGE INSTRUCTIONS:
Store below 25°C.
KEEP OUT OF REACH OF CHILDREN.
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