| Application: | Internal Medicine |
|---|---|
| Usage Mode: | for Injection |
| Suitable for: | Elderly, Adult |
| State: | Liquid |
| Shape: | for Injection |
| Type: | Western Medicines |
| Samples: |
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| Customization: |
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Indications:
For use in patients requiring supplemental potassium therapy.
Dosage and Administration:
The goal of potassium replacement therapy is to elevate the plasma concentration of the ion to within the normal range.
Dose per day: Since the normal dietary intake of potassium is 50 to 100mmol daily, it is rare that a larger amount is required during potassium replacement therapy.
Precautions & Warning:
Administration
• Only use with specialist advice
• ECG should be used throughout and monitored continuously
• High concentrations of potassium cause serious cardiotoxicity, so the concentration of the solution should not exceed 3g (40mmol)/L and the diluted solution given slowly
• Initially do not use with glucose infusions - glucose may further decrease potassium levels
Other concurrent treatment
• Extreme caution in patients on potassium sparing diuretics and other drugs that may increase potassium
• Glucose infusion
Monitoring
• Continuous ECG monitoring - see above Administration
• Regular potassium levels especially in patients with renal impairment
Underlying conditions
• Dehydration must be corrected to ensure adequate urinary output (and potassium excretion)
• Where renal excretion of potassium or cellular uptake deficient - life threatening hyperkalaemia can occur with standard doses
• Extreme caution with extensive tissue destruction (eg burns)
• Extreme caution in cardiac disease
Storage instructions:
Keep in outer carton. Do not store above 25°C.
| Testing terms | Standards | Results |
| Characteristic | A clear, colourless liquid | A clear, colourless solution |
| pH | 5.0~7.0 | 5.6 |
| Clarity of solution | A clear liquid | Complies |
| Color of solution | A colorless liquid | Complies |
| Sterility | Sterile | Sterile |
| Bacterial Endotoxin | <0.12EU/mg | Complies |
| Filling Volume | Not less than the labeled volume | Complies |
| Visible particles | Practically free from particles | Complies |
| Subvisible particles | ≥10μm:≤6000/Ampoule ≥25μm:≤600/Ampoule |
35/Ampoule 3/Ampoule |
| Assay | 95.0%-105% | 99.4% |
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