GMP Certified Anti-Malarial Medicine Arteether Injection 150mg

• Application: Internal Medicine
• Usage Mode: Injection
• Suitable for: Elderly, Children, Adult
• State: Liquid
• Shape: Injection
• Type: Organic Chemicals
• Model NO.: AMC14052-01
• Pharmaceutical Technology: Chemical Synthesis
• Registration: Available
• OEM/ODM: Support
• Shelf-Life: 3 Years
• Transport Package: 3′s/Box, 10boxes/Middle Box
• Specification: 150MG/2ML
• Trademark: Medipharm, OEM
• Origin: China
• HS Code: 3004500000
• Production Capacity: 50000boxes/Batch

Product Description

 

ARTEETHER INJECTION

DESCRIPTION:
TERTEL-150INECTION( Areether) is a synthetic derivative of artemisinin, a product of Chinese plant.

Artemisin annua.
TERTEL-IsINICTION (Arteether) is fast acting blood schizonticide specifically indicated for the treat of chloroquine resistant P. falciparum malaria and cerebral malaria cases.
TERTEL-150 INJECTION (Arteether ) is developd by Central Drug Research Institute(C D.R.I.),Lucknow, and Themis Medicare Limited after extensive preclinical clinical and toxicological studies

COMPOSITION:
Each 2ml ampoule of TERTEL-150 INECTION contains:
Arteether…150mg.

PHARMACOLOGY:   
Arteether is fast acting blood schizonticidal agent for P. falciparum Malaria at the erythrocytic satge.
Arteether is concentrated in parasitized erythrocytes. The functional group responsible for antimalarial activity of Arteether is "endoperoxide bridge". The researchers believe that iron from the digested of the parasite's victim reduces this bridge releasing a highly reactive free radical iron (V) oxo species which rips apart the parasitic cells,
It is proposed that Arteether inhibits the protein synthesis and alter the ribosomal organisation and endoplasmic reticulum.
Arteether also acts on the membranes of the parasites through lipid peroxidation

PHARMACOKINETICS:
Main metabolite of Arteether is Dihydroartemisinin. The half life of Dihydroartemisinin Is more than 20 hours. The elimination of the drug is through hepatic metabolism and gets eliminated at a low rate as compared to other artemisinin derivatives.

INDICATIONS   
TERTEL-150INJECTION( Arteether) is indicated for use in severe Pfalciparum malaria including cerebral and as second line treatment in cholroquine.

CONTRAINDICATION  
TERTEL-150 INJECTION (Arteether) is contraindicated in patients hypersensitive to artemisinin derivatives.

Storage instructions:
Store below 25ºC. Protect from moisture. Keep out of reach of children.