| Application: | Internal Medicine |
|---|---|
| Usage Mode: | For oral administration |
| Suitable for: | Elderly, Children, Adult |
| State: | Solid |
| Shape: | Tablet |
| Type: | Western Medicines |
| Samples: |
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| Customization: |
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Indications:
Metronidazole is indicated in adults and children for the following indications:
1) Prevention of post-operative infections due to anaerobic bacteria, particularly species of bacteroids and anaerobic streptococci.
2) The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis and post-operative wound infections from which pathogenic anaerobes have been isolated.
3) Urogenital trichomoniasis in the female (Trichomonas vaginalis), and in man.
4) Bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginosis or Gardnerella vaginalis).
5) All forms of amoebiasis (intestinal and extra-intestinal disease and asymptomatic cyst passers).
6) Giardiasis.
7) Acute ulcerative gingivitis.
8) Acute dental infections (eg acute pericoronitis and acute apical infections)
9) Anaerobically-infected leg ulcers and pressure sores.
10) Treatment of Helicobacter pylori infection associated with peptic ulcer as part of triple therapy.
Dosage and Administration:
Metronidazole Tablets should be taken during or after meals, swallowed with water and not chewed.
Elderly: Caution is advised in the elderly, particularly at high doses, although there is limited information available on modification of dosage.
Storage instructions:
Store below 25°C. Protect from light.
| Testing terms | Standards | Results |
| Description | Canary yellow, circular tablets | Complies |
| Identification | Metronidazole: Positive | Complies |
| Uniformity of weight | ±5.0% of the average weight | Complies |
| Disintegration | ≤30min | 5min |
| Friability | ≤1.0%w/w | Complies |
| Related substances | To comply with BP2009 | Complies |
| Assay | 95.0%-105.0% | 99.4% |
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